The website, www.tourism2012games.org, will be launched tomorrow during British Tourism Week at the Best of Britain and Ireland event at Olympia.
It will include business advice and access to products and services from London 2012 UK partners BT and Lloyds TSB.
The website will also offer marketing guidance including a brand-protection guide for communicating Olympics-related products and services to clients.
Visit Britain chief executive Sandie Dawe said: "There's a potential £2.1bn benefit at stake, so with little over two years to go, we aim to make tourism businesses aware of the tourism opportunities and challenges. The new website will help the industry understand how it can benefit from the Games."