Located on Waterloo Road, the property offers 144 standard rooms, 32 deluxe rooms, and the Waterloo suite, which overlooks the London Eye.
H10 London Waterloo also offers four meeting rooms with capacity for 55 delegates, and there is free wi-fi throughout the property.
Among the hotel's leisure facilities are the Circus Bar, the Three O Two restaurant, which serves Mediterranean and international cuisine, and the Despacio Beauty Centre, which has a sauna, fitness room and hydromassage shower.
H10 London Waterloo is the group's first property outside Spain. The H10 Berlin Ku'Damm is due to open in the final quarter of this year.