The Scottish capital was rated ahead of Brussels and Glasgow in the study, which was based on the cost of holding a typical association meeting and exhibition for 1,500 delegates, accommodation for 1,300 and a gala dinner for 1,000. Edinburgh quoted a cost of £624,558, which was £25,000 less than second-placed Brussels.
Other cities considered in the review were Paris, Vienna, Barcelona, Singapore, Hong Kong, Geneva and New York.
Edinburgh Convention Bureau (ECB) chief executive Sue Stuart said: "At a time when costs are a key factor in the decisions taken by associations about where to hold their events, it's important for a destination that we are seen to be providing value for money."
According to new figures, the ECB recorded 23 event bookings in the month up to 10 November, which will attract up to 4,600 delegates to the Scottish capital and generate 5.1m for the local economy.
The wins include a major NHS Scotland conference and a Financial Services Authority meeting, both in 2010.