Scandinavian airline Primera Air has ceased all operations and filed for bankruptcy.
It flew several routes from Stansted and Birmingham airports, announcing in March that it was adding New York and Boston to its list of destinations.
As recently as 12 September, the company was tweeting plans to start direct flights from Madrid to several American cities.
People who have booked flights with Primera are being advised to find alternative routes.
A statement on the Primera Air website said: "On behalf of the Primera Air team, we would like to thank you for your loyalty. On this sad day we are saying goodbye to all of you.
"Please visit primeraair.com for further updates in next few days. Tour operator passengers are kindly advised to address their tour operators and agents for further information and action."
Meanwhile, Ryanair shares have dropped more than 12% in value, with chief executive Michael O’Leary blaming lower passenger traffic and fewer forward bookings because of staff strikes.
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