China’s Eastern Airlines will begin flying from London Gatwick to Shanghai from 7 December.
The new direct long-haul route is expected to ferry more than 70,000 travellers each year between the UK and China.
The outbound flights will take off three times a week and land at Shanghai Pudong Airport.
"I’m delighted to welcome China Eastern to Gatwick and look forward to the start of this vital new link to Shanghai which, like London, is undoubtedly one of the world’s most important cities and business hubs," said Stewart Wingate, CEO of Gatwick Airport.
"It will be popular with business passengers travelling between the two economic centres, as well as leisure passengers keen to sample the excitement of China’s largest city."
Earlier this year, Hainan Airlines announced direct flights from China to Scotland and Ireland.
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