The 364-bedroom hotel is Hilton's first mid-market Garden Inn branded property to launch in the London area and is situated around two kilometres from Heathrow Terminal 4.
It is the third property to rebrand following a franchise agreement between Hilton Worldwide and Jurys Inn, which owns and manages the hotel.
The hotel offers seven meeting rooms with more than 176sqm of meeting space for up to 60 people, complimentary wi-fi, and a 24-hour business centre.
Adrian Kurre, global head, Hilton Garden Inn, said: "It is testament to the brand’s growing popularity that we are now open at Europe’s busiest transport hub, and we’re excited to bring Hilton Garden Inn to the London region."
John Brennan, CEO, Jurys Inn, added: "We are delighted to announce the rebrand of our Heathrow Jurys Inn hotel under the Hilton Garden Inn brand. With our hotel’s prime location within easy reach of the UK’s largest airport; we look forward to continuing to provide an extended international customer base with our stand-out customer service."
Heathrow Airport is Europe’s busiest airport by passenger volume, serving 180 destinations in 85 countries globally. The hotel is connected to central London via Hatton Cross underground station.