Chambers Travel Group has also won £8m in annual incremental SME business in the past 12 months.
The events and travel agency's new appointments are Daniel Von Weihe, who has joined as executive vice president business development, with Anthony Elliott joining as vice president of sales EMEA.
Elliott spent four years at American Express as senior business development manager UK & Ireland before joining HRS as head of corporate sales in 2010.
Chambers Travel Group has also promoted Matthew Heymans to the role of vice president of international sales and Jane Worrow to the role of director of UK sales. Worrow will be responsible for strategic opportunities at the agency.
Chris Thelen, chief executive officer of Chambers Travel Group, said: "Over the last 12 months, Chambers has increased annual sales from large-scale clients by £15.6m and also won £8m in annual incremental SME business.
"The restructuring of our sales operations and these high-calibre appointments will enable Chambers to focus on our growth markets and continue expanding in the UK, Europe and US."