Henderson will take up the newly created role of new business manager, while England-McTaggart will join the company as account development executive.
England-McTaggart joins from American Express, where she had been a senior business travel consultant since 2010. Henderson was previously business devlopment officer for the Chartered Institute of Housing.
Both Henderson and England-McTaggart will report to Conference Care head of sales Pauline Beattie.
On the new appointments, Beattie said: "The expansion of the team and investment from the company into our sales hub is a real testament to what we have already achieved, and my new team are the perfect combination with which to continue driving our success."
Conference Care launched into the Scottish market in 2005 following a succession of new business wins and development to its contracted customer base north of the border.