The agency is expecting to launch the Hong Kong office in the spring, with a team of two staff members including one focused on business development.
W&O Events managing director Sallie Coventry said: "This is a really exciting start to the year for W&O. Our planned expansion into Asia Pacific will help improve our position in this growing market.
"It further underpins our global reach and capability to serve our international client base while reaffirming our group ethos of global commitment to excellence."
The expansion follows the launch of W&O’s Middle East office, which opened in Dubai in October 2012.
Coventry added that further growth was expected moving into 2014.
The expansion of W&O into Asia Pacific is part of its owner Choice One’s growth strategy to represent both the events and medical communications businesses alongside the existing clinical research organisation in Asia.