Thompson, who has been working for Line Up on a freelance basis for the past year, has experience in designing retail, exhibition and brand environments for clients including Ferrari, Blackberry, Estee Lauder, Barclays and Shell.
He worked with Line Up on a series of pan-European events for Volvo this summer, before being appointed in the creative director role, replacing Ben Rakison, who has left to go travelling.
Line Up managing director Rob Leach said: "Neil brings with him an outstanding portfolio of work and is brimming with creative ideas. After working with us on a series of pan-European Volvo events this summer, he has once again proved that he is an agile creative talent, skilled at devising effective and memorable brand environments."
Prior to going freelance, Thompson worked at Wood Design, the Button Group and at MICE International.
Thompson said: "It feels very natural to move into a permanent role at Line Up. The agency has a strong reputation for delivering events and experiences that transform the way people think, act and feel. This is what I love about what I do and it is exciting to now be at the creative heart of a forward-thinking and tight-knit team."
As well as acting as agency lead on live creative projects, Thompson will also play a role in helping develop Line Up’s digital portfolio.