The 14-room hotel on the edge of Loch Lomond is 24 miles from Glasgow and has a self-contained events and conference suite.
The Inchonnachan suite is in a private garden next to the hotel, and can accommodate 100 delegates for sit-down dining and 200 for other events.
Loch Lomond Arms Hotel general manager Alastair Borland said: "Our overarching aim is create an authentic Scottish experience for visitors, giving them a warm welcome from the moment they walk through the door."
Local activities from the hotel, which is in the Loch Lomond National Park, include wildlife watching, boating, golf and fishing, as well as whisky distilleries and a brewery.
Luss Estates Company chairman Sir Malcolm Colquhoun said: "The opening of the hotel is the culmination of several years’ hard work. It also marks the beginning of putting Luss back on the map not just as an appealing tourist destination, but as a vibrant village with much to offer in terms of job opportunities and lifestyle appeal."