Around 900 delegates are expected to attend the three-day political event, contributing more than £800,000 to the local economy.
The conference will include a training day for delegates on 20 September and a gala dinner the following evening. Guest speakers will address delegates at the conference, including Wolfson Prize-winning economist Roger Bootle and broadcaster and songwriter Mike Read.
Meet Birmingham, the official business tourism programme for the city, is facilitating the conference through the Birmingham Convention Bureau (BCB).
By the end of 2012, Birmingham will have welcomed nine conferences in five years.
Ian Taylor, commercial director at Marketing Birmingham, said: "Birmingham consistently delivers successful events, which is why it remains one of the busiest and most popular UK destinations in the conferencing sector, particularly for political parties. Our recent track record of hosting events of this nature is unparalleled and is a tribute to the sustained hard work of our many conference venues, accommodation, restaurants and transport providers, who showcase the city and its excellent facilities at their very best."