The Olympic sponsor's dedicated venue will be erected in Westfield Stratford and will serve as its official base for the duration of the Games.
Deloitte House will have capacity for 180 delegates and a private viewing deck overlooking the Olympic Park.
Sportsworld will be the partner company for running hospitality at the venue as well as staff trips to Games events.
"Many of our hospitality tickets have been awarded to staff as part of competitions and challenges we have run internally," said Deloitte UK events manager Faye Carter.
Deloitte House will hold internal staff and client events in the run-up and during the Games, as well as projects with schools, charities and the local community.
Sportsworld, which counts brands including Samsung, Microsoft and 3M among its client base, is an authorised sales agent for Prestige Ticketing, the official on-site hospitality partner for London 2012.