Nightingale's previous roles include director of communications at P&MM and director of communications at Grass Roots Group, Trin.
Fay Sharpe, Zibrant’s managing director of sales and marketing, said: "We are sad to see such a great member of staff leave. She had such a positive impact on all of us here."
Nightingale has worked at Motivcom, which owns Zibrant and P&MM, for more than 11 years.
MCM commercial director Robert Kenward said: "Debra's expertise in the events sector is extremely well respected and she is joining at an exciting time. We’re all looking forward to working with Debra to further enhance our services to our existing portfolio as well as assisting us with new client opportunities."
Nightingale recently took part in Zibrant's episode of C&IT Cribs.