The announcement comes as Visit London, Think London and Study London prepare to join together, under the working title Promote London.
Chatterjee, who joined Visit London in 2008, said: "Hosting the 2012 Olympic and Paralympic Games next year means that there has never been a bigger opportunity for London’s tourism industry to showcase itself to the world, and I leave secure in the knowledge that we have delivered the strategy to ensure that there will be a significant economic legacy from the Games for the tourism industry."
Visit London chair Tamara Ingram added: "I would personally like to thank Sally for her outstanding contribution. Since its establishment in 2003, Visit London has delivered an incremental £2bn in revenue for the nation and in the last four years alone, Visit London has developed a number of award winning campaigns to promote the capital to leisure and business visitors."
Sally Chatterjee (above).