Mitchell, Buse’s daughter has already been responsible for the day to day running of the DMC since 2007, when she was appointed managing partner.
Buse said: "As founding partner I am very proud to have played an integral part in the creation of Destinations Unlimited. I am really going to miss both working with my team and of course the events industry in general, in which I have been extremely privileged to have made some great friends."
Mitchell added: "David is leaving on a high and I am extremely proud of the company that he has created. I am going to miss working with him, but I really look forward to continuing to take the company forward; building rapport with both new and existing clients and providing ongoing representation of reputable DMCs."