KPMG has been appointed administrators for the properties, which include the Academy, the Colonnade and Threadneedles hotels in London, the Glasshouse in Edinburgh and Quebecs in Leeds.
"The hotels have gone into administration because of their heavy debt burdens," a KPMG spokeswoman told C&IT. "As they have traditionally traded well, we're hopeful of a sale."
The Eton Collection’s 42 The Calls in Leeds and the Scotsman in Edinburgh are not within the parameters of the administration, KPMG said.
The group employs around 250 staff and no redundancies have been made to date.
KPMG joint administrator and restructuring partner Jane Moriarty said: "We are continuing to trade the business while we assess the position of the hotels. Historically, however, the hotels have traded successfully and are well regarded at the luxury end of the market so we are hopeful of securing a successful resolution to this situation."
Eton Collection managing director Peter Tyree told C&IT last March: "Trading is a bit touchy. It is down on last year but our budget predictions allowed for that. In the West End we're on target but in the City, the corporate market has got much weaker."