The event, from 25-29 October, is expected to attract more than 3,000 delegates from 125 countries, generating around £7.8m in economic benefit for the city.
The five-day scientific programme will present the latest developments in the inter-related fights against tuberculosis, HIV, lung disease and non-communicable diseases.
Mayor of Liverpool Joe Anderson said the win is a "huge coup" for Liverpool and "puts the city in the spotlight as a global leader in this field".
The conference is led by the International Union Against Tuberculosis and Lung Disease [The Union].
Professor Bertie Squire, past president and board member of The Union and professor at Liverpool School of Tropical Medicine (LSTM), said: "The Union’s decision to host its World Conference in Liverpool is not only a recognition of our outstanding conference host city but also an acknowledgement of the leading research being conducted here in the field of TB and wider lung health."
Kerrin MacPhie, director of sales at ACC Liverpool, which recently revealed a new corportate brand, added: "Professor Squire, supported by the team, has driven this successful bid. This is a great example of Team Liverpool’s winning formula - from the academic expertise within the city, to destination support and world-class conference facilities."
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